The Timothy O'Keeffe correspondence documents the Irish authors he worked with from 1958 to 1971. It contains letters to and from O'Keeffe, as well as news clippings and a few manuscripts that were sent as enclosures.

The correspondence primarily documents the professional relationships that O'Keeffe, as an editor, had with J.P. Donleavy, Michael Farrell, Sean O'Casey, James Plunkett, and Francis Stuart. The letters reveal O'Keeffe's editorial style... and the relationships he built with the authors with whom he worked. The most voluminous correspondence is with: J.P. Donleavy, discussing the Italian publication of Donleavy's The Ginger Man; James Plunkett, discussing some of O'Keeffe's current projects and the lives of mutual friends; and Francis Stuart, detailing the difficult publication and editing process for the manuscript that was to become Stuart's Black List, Section H.